Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methylsulfonyl)phenylamino)pyrimidin-4-yl)amino)acetonitrile
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 PubChem ID
CID: 52949394
Canonical SMILES
CS(=O)(=O)c1cccc(Nc2nccc(n2)N(CC#N)c2c3OCOc3ccc2Cl)c1
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Compound Formula C20H16ClN5O4S
Compound Structure
Protein Name
 Protein Info 
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 95 nM