Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,4-Pyrimidine derivative, 28
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 PubChem ID
CID: 25011729
SID: 57289015
Canonical SMILES
CS(=O)(=O)c1cccc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)c1
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Compound Formula C18H15ClN4O4S
Compound Structure
Protein Name
 Protein Info 
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 187 nM
   TI
   LI
   LO
   TS
2
IC50 = 190 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25 nM
2 IC50 = 90 nM