Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-Fluoro-5-(2-(pyridin-2-yl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]-pyrazin-7(8H)-yl)benzonitrile
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 PubChem ID
CID: 46932196
SID: 99439019
Canonical SMILES
Fc1cc(cc(c1)N1CCn2nc(nc2C1)-c1ccccn1)C#N
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Compound Formula C17H13FN6
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 346 nM
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