Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-fluoro-5-(2-(pyridin-2-yl)-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)benzonitrile
    Show/Hide
 PubChem ID
CID: 46932105
SID: 99438924
Canonical SMILES
Fc1cc(cc(c1)N1CCn2cc(nc2C1)-c1ccccn1)C#N
    Show/Hide
Compound Formula C18H14FN5
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 153 nM
   TI
   LI
   LO
   TS