Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3-chloro-4-fluorophenyl)(4-fluoro-4-((methyl((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone
    Show/Hide
 PubChem ID
CID: 49780600
SID: 103053088
Canonical SMILES
CN(Cc1ccc(C)cn1)CC1(F)CCN(CC1)C(=O)c1ccc(F)c(Cl)c1
    Show/Hide
Compound Formula C21H24ClF2N3O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 8.6 nM
   TI
   LI
   LO
   TS