Brief Information of the Compound and Protein
Compound Name
(4-Fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-furan-3-yl-methanone
    Show/Hide
PubChem ID
CID: 42606461
SID: 74379422
Canonical SMILES
Cc1ccc(CNCC2(F)CCN(CC2)C(=O)c2ccoc2)nc1
    Show/Hide
Compound Formula C18H22FN3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 240 nM
   TI
   LI
   LO
   TS