Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride
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 PubChem ID
CID: 44395741
SID: 103055129
Canonical SMILES
Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccc(Cl)cc1
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Compound Formula C20H22ClFN2O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 61 nM
   TI
   LI
   LO
   TS
2
Ki = 63 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Kd = 28.18 nM
   TI
   LI
   LO
   TS
2
Ki = 29.51 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 253.3 nM
2 Ki = 253.5 nM
3 Ki = 254 nM