Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(2-hydroxy-3-(1-(5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propoxy)-2-(hydroxymethyl)phenol
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 PubChem ID
CID: 24936882
SID: 53835001
Canonical SMILES
OCc1cc(OCC(O)CNC2CCN(CC2)c2ncnc3scc(-c4cccs4)c23)ccc1O
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Compound Formula C25H28N4O4S2
Compound Structure
Protein Name
 Protein Info 
Beta-3 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P13945
Gene Name
ADRB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
Ki = 62 nM
   TI
   LI
   LO
   TS