Brief Information of the Compound and Protein
Compound Name
2-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)cyclopent-1-enecarboxamide
    Show/Hide
PubChem ID
CID: 49864986
Canonical SMILES
Fc1ccc(NC(=O)C2=C(CCC2)c2nc(Nc3cc(n[nH]3)C3CC3)c3cccn3n2)cn1
    Show/Hide
Compound Formula C23H21FN8O
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000899 IGFSal Homo sapiens (Human)  1
1
IC50 = 237 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 32 nM