Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(2-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl)(6-fluoropyridin-3-yl)methanone
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 PubChem ID
CID: 25101485
SID: 56421214
Canonical SMILES
Fc1ccc(cn1)C(=O)N1CCC[C@H]1c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1
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Compound Formula C22H21FN8O
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000899 IGFSal
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 162 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM