Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8592579, 104
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 PubChem ID
CID: 24785538
SID: 123055432
Canonical SMILES
C[C@]1(CCCN1c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1)C(=O)Nc1ccc(F)nc1
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Compound Formula C23H24FN9O
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000899 IGFSal
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.8 nM
2 IC50 = 2 nM
3 IC50 = 8.4 nM
4 Kd = 0.9615 nM