Brief Information of the Compound and Protein
Compound Name
(R)-(3-methyl-4-(4-(pyridin-2-yl)phthalazin-1-yl)piperazin-1-yl)(phenyl)methanone
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PubChem ID
CID: 49862313
Canonical SMILES
C[C@@H]1CN(CCN1c1nnc(-c2ccccn2)c2ccccc12)C(=O)c1ccccc1
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Compound Formula C25H23N5O
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000336 HEPM Homo sapiens (Human)  1
1
IC50 = 57 nM
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