Brief Information of the Compound and Protein
Compound Name
2-(3,4-dihydro-2H-quinolin-1-yl)-9,10-dimethoxy-6,7-dihydropyrimid[6,1-a]isoquinolin-4-one
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PubChem ID
CID: 663831
Canonical SMILES
COc1cc2CCn3c(cc(nc3=O)N3CCCc4ccccc34)-c2cc1OC
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Compound Formula C23H23N3O3
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 35640 nM
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