Brief Information of the Compound and Protein
Compound Name
AMITIFADINE HYDROCHLORIDE
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PubChem ID
CID: 11658655
SID: 16762225
Canonical SMILES
Clc1ccc(cc1Cl)[C@@]12C[C@@H]1CNC2
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Compound Formula C11H11Cl2N
Compound Structure
Protein Name
Sodium-dependent noradrenaline transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
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SLC06 neurotransmitter transporter family
Uniprot ID
P23975
Gene Name
SLC6A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 71.4 nM
   TI
   LI
   LO
   TS
CL000009 LLC-PK1 Sus scrofa (Pig)  1
1
Ki = 147.91 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22.8 nM