Brief Information of the Compound and Protein
Compound Name
10-(4-methylphenyl)sulfonyl-N-(thiophen-2-ylmethyl)-5-thia-1,8,11,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-7-amine
    Show/Hide
PubChem ID
CID: 16019312
Canonical SMILES
Cc1ccc(cc1)S(=O)(=O)c1nnn2c3ccsc3c(NCc3cccs3)nc12
    Show/Hide
Compound Formula C19H15N5O2S3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS