Brief Information of the Compound and Protein
Compound Name
3-(phenylsulfonyl)-N-(thiophen-2-ylmethyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine
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PubChem ID
CID: 16019576
SID: 99376997
Canonical SMILES
O=S(=O)(c1nnn2c3ccsc3c(NCc3cccs3)nc12)c1ccccc1
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Compound Formula C18H13N5O2S3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 3.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 110 nM
   TI
   LI
   LO
   TS
3
Ki = 1.7 nM
   TI
   LI
   LO
   TS