Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[4-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-(4-methoxypiperidin-1-yl)methanone
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 PubChem ID
CID: 46906793
Canonical SMILES
COC1CCN(CC1)C(=O)c1ccc(cc1)-c1cnc2NCCN(Cc3cc(Cl)ccc3C(F)(F)F)c2c1
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Compound Formula C28H28ClF3N4O2
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000300 Karpas-299
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM