Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5S,12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene
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 PubChem ID
CID: 46180399
SID: 96033465
Canonical SMILES
C[C@H]1Cc2ccc3C[C@H]4N(C)CCc5cccc(c45)-c3c2O1
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Compound Formula C20H21NO
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
2
Ki = 45.3 nM
   TI
   LI
   LO
   TS