Brief Information of the Compound and Protein
Compound Name
(4-(4-(3,4-dichlorophenyl)phthalazin-1-yl)piperazin-1-yl)(phenyl)methanone
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PubChem ID
CID: 46890991
Canonical SMILES
Clc1ccc(cc1Cl)-c1nnc(N2CCN(CC2)C(=O)c2ccccc2)c2ccccc12
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Compound Formula C25H20Cl2N4O
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000336 HEPM Homo sapiens (Human)  2
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 17.3 nM
   TI
   LI
   LO
   TS