Brief Information of the Compound and Protein
Compound Name
(S)-(2-methyl-4-(4-(pyridazin-1(6H)-yl)phthalazin-1-yl)piperazin-1-yl)(phenyl)methanone
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PubChem ID
CID: 46891300
Canonical SMILES
C[C@H]1CN(CCN1C(=O)c1ccccc1)c1nnc(N2CC=CC=N2)c2ccccc12
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Compound Formula C24H24N6O
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000336 HEPM Homo sapiens (Human)  1
1
IC50 = 2340 nM
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