Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[4-[(2,5-Difluorophenoxy)methyl]-2-({[(1S)-1-(3,5-dimethylphenyl)-3-methylbutyl]amino}carbonyl)phenyl]-propanoic acid
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 PubChem ID
CID: 46887126
Canonical SMILES
CC(C)C[C@H](NC(=O)c1cc(COc2cc(F)ccc2F)ccc1CCC(O)=O)c1cc(C)cc(C)c1
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Compound Formula C30H33F2NO4
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P30557
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
2
Ki = 1.4 nM
   TI
   LI
   LO
   TS