Brief Information of the Compound and Protein
Compound Name
3-(2-({[(1R)-1-(3,5-Dimethylphenyl)-3-methylbutyl]-amino}carbonyl)-4-{[(6-methylpyridin-3-yl)oxy]methyl}-phenyl)propanoic acid
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PubChem ID
CID: 10051189
SID: 15034750
Canonical SMILES
CC(C)C[C@@H](NC(=O)c1cc(COc2ccc(C)nc2)ccc1CCC(O)=O)c1cc(C)cc(C)c1
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Compound Formula C30H36N2O4
Compound Structure
Protein Name
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P30557
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 5.4 nM
   TI
   LI
   LO
   TS
2
Ki = 0.48 nM
   TI
   LI
   LO
   TS