Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
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 PubChem ID
CID: 444
SID: 15196401
Canonical SMILES
CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1
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Compound Formula C13H18ClNO
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent dopamine transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
Q01959
Gene Name
SLC6A3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 658 nM
   TI
   LI
   LO
   TS
2
IC50 = 660 nM
   TI
   LI
   LO
   TS
3
IC50 = 945 nM
   TI
   LI
   LO
   TS
4
IC50 = 1200 nM
   TI
   LI
   LO
   TS
5
Ki = 871 nM
   TI
   LI
   LO
   TS
CL000020 Neuro-2a
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 1567 nM
   TI
   LI
   LO
   TS
2
Ki = 441 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 330 nM
2 IC50 = 550 nM
3 IC50 = 2900 nM