Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}Quinoline
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 PubChem ID
CID: 12004114
SID: 17503377
Canonical SMILES
COc1cc(N2CCN(CC2)C2CCN(CC2)c2c(F)ccc3cccnc23)c2ncccc2c1
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Compound Formula C28H30FN5O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 331 nM
   TI
   LI
   LO
   TS
2
Ki = 276 nM
   TI
   LI
   LO
   TS