Brief Information of the Compound and Protein
Compound Name
L-706,000
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PubChem ID
CID: 9934294
SID: 14907354
Canonical SMILES
CS(=O)(=O)Nc1ccc2OC3(CCN(CC3)[C@@H]3CCc4cc(ccc4C3)C#N)C[C@@H](O)c2c1
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Compound Formula C25H29N3O4S
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 21.38 nM
   TI
   LI
   LO
   TS
2
IC50 = 670 nM
   TI
   LI
   LO
   TS