Brief Information of the Compound and Protein
Compound Name
3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-oxazolidin-3-yl}benzonitrile
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PubChem ID
CID: 46830123
SID: 99207773
Canonical SMILES
CC(C)(C)c1ccc(OC[C@@H]2CN(C(=O)O2)c2cccc(c2)C#N)cc1
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Compound Formula C21H22N2O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 82 nM
   TI
   LI
   LO
   TS
2
EC50 = 4900 nM
   TI
   LI
   LO
   TS