Brief Information of the Compound and Protein
Compound Name
2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3,4-(difluoro)phenyl]-1H-pyrrol-3-acetic acid
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PubChem ID
CID: 46229714
Canonical SMILES
Cc1c(CC(O)=O)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(F)c(F)c1
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Compound Formula C20H17F2NO4S
Compound Structure
Protein Name
Prostaglandin G/H synthase 2
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
Q05769
Gene Name
PTGS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000158 J774 Mus musculus (Mouse)  3
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
2
IC50 = 70000 nM
   TI
   LI
   LO
   TS
3
IC50 = 98000 nM
   TI
   LI
   LO
   TS