Brief Information of the Compound and Protein
Compound Name
6-chloro-2-(4-methylpiperazin-1-yl)-N-(2-pyrrolidin-1-ylsulfonylethyl)quinazolin-4-amine
    Show/Hide
PubChem ID
CID: 45379805
SID: 93371404
Canonical SMILES
CN1CCN(CC1)c1nc(NCCS(=O)(=O)N2CCCC2)c2cc(Cl)ccc2n1
    Show/Hide
Compound Formula C19H27ClN6O2S
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 17.78 nM
   TI
   LI
   LO
   TS