Brief Information of the Compound and Protein
Compound Name
6-chloro-2-(4-methylpiperazin-1-yl)-N-(1,3-thiazol-5-ylmethyl)quinazolin-4-amine
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PubChem ID
CID: 25178555
SID: 57284746
Canonical SMILES
CN1CCN(CC1)c1nc(NCc2cncs2)c2cc(Cl)ccc2n1
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Compound Formula C17H19ClN6S
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 107.15 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 107.15 nM
   TI
   LI
   LO
   TS