Brief Information of the Compound and Protein
Compound Name
6-chloro-N-methyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
    Show/Hide
PubChem ID
CID: 25178937
SID: 57285140
Canonical SMILES
CNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1
    Show/Hide
Compound Formula C14H18ClN5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 79.43 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 70.79 nM
   TI
   LI
   LO
   TS