Brief Information of the Compound and Protein
Compound Name
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(2-methylpyridin-4-yl)-1,3,4-thiadiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
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PubChem ID
CID: 46229316
SID: 104174984
Canonical SMILES
Cc1cc(ccn1)-c1nnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1
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Compound Formula C21H22ClN3O5S
Compound Structure
Protein Name
Sodium/glucose cotransporter 2
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC05 family of sodium-dependent glucose transporters
Uniprot ID
P31639
Gene Name
SLC5A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 36.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 36.4 nM