Brief Information of the Compound and Protein
Compound Name
4-{(1S)-1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}-carbonyl)amino]ethyl}benzoic acid
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PubChem ID
CID: 24952927
SID: 56250752
Canonical SMILES
C[C@H](NC(=O)c1c(C)sc(C)c1Cc1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(O)=O
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Compound Formula C24H22F3NO3S
Compound Structure
Protein Name
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS