Brief Information of the Compound and Protein
Compound Name
6-phenyl-2-(piperidin-1-yl)-7-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)pyrido[2,3-d]pyrimidine
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PubChem ID
CID: 11542208
SID: 16716980
Canonical SMILES
C(N1CCC(CC1)c1nnc([nH]1)-c1ccccn1)c1ccc(cc1)-c1nc2nc(ncc2cc1-c1ccccc1)N1CCCCC1
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Compound Formula C37H37N9
Compound Structure
Protein Name
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A Homo sapiens (Human)  1
1
IC50 = 229 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 93 nM