Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3,3-difluoropyrrolidin-1-yl)-6-phenyl-7-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)pyrido[2,3-d]pyrimidine
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 PubChem ID
CID: 11643074
SID: 16746296
Canonical SMILES
FC1(F)CCN(C1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1
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Compound Formula C36H33F2N9
Compound Structure
Protein Name
 Protein Info 
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000375 C-33 A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 462 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 252 nM