Brief Information of the Compound and Protein
Compound Name
(7R,9S)-7-(((3S,4R)-3-(hydroxymethyl)-4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol
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PubChem ID
CID: 11372427
SID: 16465655
Canonical SMILES
Cc1ccccc1[C@@H]1CCN(C[C@@H]2CCc3cccnc3[C@@H](O)C2)C[C@H]1CO
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Compound Formula C24H32N2O2
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 7.3 nM
   TI
   LI
   LO
   TS
2
Ki = 4.3 nM
   TI
   LI
   LO
   TS