Brief Information of the Compound and Protein
Compound Name
(Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid
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PubChem ID
CID: 5329099
SID: 14874233
Canonical SMILES
Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
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Compound Formula C18H18N2O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 135 nM
2 IC50 = 680 nM
3 IC50 = 2400 nM
4 IC50 = 2430 nM