Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BDBM50242742
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 PubChem ID
CID: 16038120
SID: 24420733
Canonical SMILES
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCC(CC1)N1CCN(C)CC1
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Compound Formula C30H40ClN7O3S
Compound Structure
Protein Name
 Protein Info 
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 554 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 500 nM
2 IC50 = 3 nM
3 IC50 = 120 nM
4 IC50 = 218 nM
5 IC50 = 536 nM
6 Kd = 2 nM
7 Kd = 4.9 nM
8 Kd = 8.2 nM
9 Kd = 8.6 nM
10 Kd = 11 nM
11 Kd = 15 nM
12 Kd = 34 nM