Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-1-(4-cyclopentylpiperidin-1-yl)-3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylthio)-4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl)propan-2-ol
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 PubChem ID
CID: 46884339
Canonical SMILES
CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)C1CCCC1)-c1ccc(c(SCCN2CCCCC2)c1)C(F)(F)F
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Compound Formula C34H50F3N5O3S2
Compound Structure
Protein Name
 Protein Info 
Cathepsin S
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P25774
Gene Name
CTSS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000147 JY
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 218 nM