Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[5-[2-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2,6-difluorobenzamide
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 PubChem ID
CID: 46886321
Canonical SMILES
CCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c(nc3sccn23)-c2cccc(NC(=O)c3c(F)cccc3F)c2)cc1
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Compound Formula C34H30F2N8OS
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000216 NCI-N87
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 69 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM