Brief Information of the Compound and Protein
Compound Name
N-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-N-[[4-(3-methylsulfonylphenyl)phenyl]methyl]benzenesulfonamide
    Show/Hide
PubChem ID
CID: 46202932
SID: 96057007
Canonical SMILES
Cc1ccccc1S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl
    Show/Hide
Compound Formula C28H25ClFNO4S2
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 3.162 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.59 nM