Brief Information of the Compound and Protein
Compound Name
1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)ethyl)-1H-pyrrolo[3,2-b]pyridin-5-yl)ethanone
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PubChem ID
CID: 45487129
SID: 96040361
Canonical SMILES
CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1ccc(Br)cc1
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Compound Formula C19H20BrN3O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 385 nM
   TI
   LI
   LO
   TS
2
Ki = 3.9 nM
   TI
   LI
   LO
   TS