Brief Information of the Compound and Protein
Compound Name
1-(4-methoxy-2-methylphenyl)-N-((R)-1-methoxybutan-2-yl)-3,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    Show/Hide
PubChem ID
CID: 45485034
Canonical SMILES
CC[C@H](COC)Nc1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C
    Show/Hide
Compound Formula C20H27N5O2
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 210 nM
   TI
   LI
   LO
   TS