Brief Information of the Compound and Protein
Compound Name
(R)-N-(4-(3,4-dimethoxyphenyl)-4-(1-oxo-4-(piperazin-1-yl)isoindolin-2-yl)butyl)-N-methylthiophene-2-sulfonamide
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PubChem ID
CID: 44597070
SID: 87329437
Canonical SMILES
COc1ccc(cc1OC)[C@@H](CCCN(C)S(=O)(=O)c1cccs1)N1Cc2c(cccc2N2CCNCC2)C1=O
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Compound Formula C29H36N4O5S2
Compound Structure
Protein Name
Urotensin-2 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
Q9UKP6
Gene Name
UTS2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000397 RMS13 Mus musculus (Mouse)  2
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
2
Ki = 49 nM
   TI
   LI
   LO
   TS