Brief Information of the Compound and Protein
Compound Name
2-ethyl-5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)isoindolin-1-one
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PubChem ID
CID: 11772069
SID: 16881233
Canonical SMILES
CCN1Cc2cc(ccc2C1=O)-c1nnn(c1C)-c1cccnc1F
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Compound Formula C18H16FN5O
Compound Structure
Protein Name
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.3 nM
   TI
   LI
   LO
   TS