Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)-2-isopropylisoindolin-1-one
    Show/Hide
 PubChem ID
CID: 11325594
SID: 16415575
Canonical SMILES
CC(C)N1Cc2cc(ccc2C1=O)-c1nnn(c1C)-c1cccnc1F
    Show/Hide
Compound Formula C19H18FN5O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS