Brief Information of the Compound and Protein
Compound Name
4-fluoro-N-methyl-N-(4-(pyrimidin-5-yl)thiazol-2-yl)benzamide
    Show/Hide
PubChem ID
CID: 45486816
Canonical SMILES
CN(C(=O)c1ccc(F)cc1)c1nc(cs1)-c1cncnc1
    Show/Hide
Compound Formula C15H11FN4OS
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS