Brief Information of the Compound and Protein
Compound Name
N-[4-[6-(ethylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-4-fluoro-N-methylbenzamide
    Show/Hide
PubChem ID
CID: 16660140
SID: 26520176
Canonical SMILES
CCNc1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(F)cc1
    Show/Hide
Compound Formula C17H16FN5OS
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 9200 nM
   TI
   LI
   LO
   TS