Brief Information of the Compound and Protein
Compound Name
N'-(5-Cyclopropyl-2H-pyrazol-3-yl)-5-fluoro-N-[(1S)-1-(4-fluorophenyl)ethyl]pyrimidine-2,4-diamine
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PubChem ID
CID: 24949094
SID: 56246853
Canonical SMILES
C[C@H](Nc1ncc(F)c(Nc2cc(C3CC3)[nH]n2)n1)c1ccc(F)cc1
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Compound Formula C18H18F2N6
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
EC50 = 17 nM
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