Brief Information of the Compound and Protein
Compound Name
(R)-3-(5-Chloro-2-((S)-1-(5-fluoropyridin-2-yl)ethylamino)-6-(5-isopropoxy-1H-pyrazol-3-ylamino)pyrimidin-4-ylamino)propane-1,2-diol
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PubChem ID
CID: 24949706
SID: 56247480
Canonical SMILES
CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)nc(NC[C@@H](O)CO)c2Cl)n[nH]1
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Compound Formula C20H26ClFN8O3
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
EC50 = 1 nM
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