Brief Information of the Compound and Protein
Compound Name
(2R)-2-[[5-Chloro-4-[(5-methylsulfanyl-2H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]-2-(4-fluorophenyl)ethanol
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PubChem ID
CID: 24949404
SID: 56247186
Canonical SMILES
CSc1cc(Nc2nc(N[C@@H](CO)c3ccc(F)cc3)ncc2Cl)n[nH]1
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Compound Formula C16H16ClFN6OS
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
EC50 = 36 nM
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